The authors studied 56 patients with cardioembolic stroke to search fo
r intracardiac thrombi by use of transesophageal and transthoracic ech
ocardiography. Forty consecutive patients were examined within four we
eks of stroke onset and the remaining 16 in the chronic stage. They al
so performed ultrafast computed tomography in 9 of them. Underlying he
art disease was present in all subjects. Anticoagulant therapy had alr
eady been started in 29 at the time of examinations. Using their own c
riteria for echocardiography, they diagnosed intracardiac thrombus in
7 cases and valvular vegetation in 1. Six thrombi were located in the
left atrial appendage, 4 of which were smaller than 10 mm in diameter.
These small thrombi were not found by either transthoracic echocardio
graphy or computed tomography. Transesophageal echocardiography appear
s to be superior to the other two methods, especially for detecting sm
all intracardiac thrombi in the left atrial appendage.