STRUCTURE-BASED DESIGN AND PHARMACOLOGICAL PROPERTIES OF POTENT SELECTIVE AND SYSTEMICALLY ACTIVE CCK-B PEPTIDOMIMETICS

Authors
ROQUES BP CORRINGER PJ DERRIEN M DAUGE V DURIEUX C
Citation
Bp. Roques et al., STRUCTURE-BASED DESIGN AND PHARMACOLOGICAL PROPERTIES OF POTENT SELECTIVE AND SYSTEMICALLY ACTIVE CCK-B PEPTIDOMIMETICS, Bioorganic & medicinal chemistry letters, 3(5), 1993, pp. 847-850
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
5
Year of publication
1993
Pages
847 - 850
Database
ISI
SICI code
0960-894X(1993)3:5<847:SDAPPO>2.0.ZU;2-K
Abstract
Selective CCK-A and CCK-B agonists and antagonists, having all the cri teria required to be administered systemically have been developed. pB C 264, a selective CCK-B agonist has permitted the in vitro and in viv o characterization of brain receptors, and has been used to establish the involvement of CCK-B receptors in anxiety-related behaviour.