Offspring of rats fed a liquid diet containing ethanol during their pr
egnancies were compared to controls on a caloric discrimination test b
eginning at 22 days of age. All pups received simultaneous choice betw
een a palatable, noncaloric diet and a similar diet containing starch.
Each diet contained a distinctive flavor. To test for flavor preferen
ce learning, pups then received an extinction test: a simultaneous cho
ice between two noncaloric diets, identical except for flavor. Prenata
l alcohol exposure had no substantial effect on the caloric discrimina
tion, and all groups preferentially ingested the starch diet on all te
st days. However, during the extinction test, alcohol-exposed pups sho
wed a significantly weaker flavor preference than control pups. These
data extend the effects of prenatal alcohol exposure on learning and i
ngestive behavior to include solid food discriminations at the time of
weaning.