COMPARISON OF A NEW AND A STANDARD SINGLE-NEEDLE DIALYSIS SYSTEM USING A MATHEMATICAL-MODEL

Two single-needle dialysis systems are compared for their hydrodynamic and kinetic behavior, the classic double-headed pump system and a new er bidirectional blood pump. First, discharges and pressures are calcu lated in a time-space grid to learn about the flow characteristics of the single-needle systems. These parameters are important for they con trol ultrafiltration and clearance rates in the artificial kidney. Als o, the influence of different artificial kidneys and expansion chamber s on the flow parameters is studied. Second, starting from these resul ts, the removal of urea and creatinine is simulated using a double-poo l model for both a normal dialysis session and an ultrashort daily aut odialysis. As a result, the use of a single marker molecule to study o r characterize solute removal is questioned. The new blood pump is abl e to perform dialysis filtering equivalently to the classic system but has its own specific advantages.