THE PARTICULAR DISTRIBUTION OF HLA-DRB1-04 AND HLA-DQB1-03 GENES AMONG HEALTHY CAUCASIANS IN WEST SIBERIA

Authors
SARTAKOVA ML KONENKOV VI KIMURA A
Citation
Ml. Sartakova et al., THE PARTICULAR DISTRIBUTION OF HLA-DRB1-04 AND HLA-DQB1-03 GENES AMONG HEALTHY CAUCASIANS IN WEST SIBERIA, Genetika, 29(4), 1993, pp. 675-680
Citations number
14
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
29
Issue
4
Year of publication
1993
Pages
675 - 680
Database
ISI
SICI code
0016-6758(1993)29:4<675:TPDOHA>2.0.ZU;2-Z
Abstract
The allelic HLA-DRB1 04 and HLA-DQB1 03 polymorphism in caucasians liv ing among the West Siberia Mongoloid aborigenes was studied. As a resu lt of our studies, it was shown that the HLA-DRB 1 0403/07 predominate s and HLA-DRB1 0404/08 is absent in the Russian population of West Sib eria, in contrast to those among Caucasians living in West Europe and North America. The frequencies of HLA-DQB1 03 alleles are similar to t hose observed among the all Caucasians. Gametic association HLA-DR4 - HLA-DQw was found for the first time in Caucasians of West Siberia.