T. Nishiyama et al., ADENOSINE PRODUCTION BY AN ADENINE REVERTANT DERIVED FROM AN INOSINE PRODUCER (INDUSTRIAL-PRODUCTION OF ADENOSINE .1.), Nippon Nogei Kagakukaishi, 67(5), 1993, pp. 843-847
An adenosine producer (an adenine revertant), Bacillus subtilis A 3-5,
was derived from an inosine producer, B.subtilis AJ-11102, which had
the genetic properties of adenine auxotrophy, xanthine auxotrophy, 8-a
zaguanine resistance, and sulfaguanidine resistance. A 3-5 produced 9
g/l adenosine f rom 80 g/l glucose in 104 h. It could be used industri
ally because productivity was high and stable.