THE HUMAN GENE FOR THE ZONA-PELLUCIDA GLYCOPROTEIN ZP3 AND A 2ND POLYMORPHIC LOCUS ARE LOCATED ON CHROMOSOME-7

Authors
VANDUIN M POLMAN JEM SUIKERBUIJK RF VANKESSEL AHMG OLIJVE W
Citation
M. Vanduin et al., THE HUMAN GENE FOR THE ZONA-PELLUCIDA GLYCOPROTEIN ZP3 AND A 2ND POLYMORPHIC LOCUS ARE LOCATED ON CHROMOSOME-7, Cytogenetics and cell genetics, 63(2), 1993, pp. 111-113
Citations number
15
Categorie Soggetti
Cytology & Histology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
63
Issue
2
Year of publication
1993
Pages
111 - 113
Database
ISI
SICI code
0301-0171(1993)63:2<111:THGFTZ>2.0.ZU;2-E
Abstract
Southern blot analysis of genomic DNA and gene-cloning experiments hav e recently shown that the human ZP3 gene is not a single-copy gene' Th e human genome harbors sequences encoding a protein of 424 amino acids and, in addition, a polymorphic locus with the potential to give rise to a probably nonfunctional polypeptide of 372 residues. In this repo rt it is shown, by screening of a panel of human x hamster hybrid cell lines, that both the ZP3 and ZP3P loci are located on human chromosom e 7.