Cm. Roberts et al., VALUE OF PULSE OXIMETRY IN SCREENING FOR LONG-TERM OXYGEN-THERAPY REQUIREMENT, The European respiratory journal, 6(4), 1993, pp. 559-562
Pulse oximetry, combined with spirometry, was evaluated as a method of
selecting chronic obstructive pulmonary disease (COPD) out-patients r
equiring definitive arterial blood gas analysis for long-term oxygen t
herapy (LTOT) assessment. A relatively high screening arterial oxygen
saturation by pulse oximetry (SaO2) level was set, in order to maximiz
e sensitivity. All 113 COPD out-patients attending the hospital clinic
over a 6 month period were screened. Sixty had a forced expiratory vo
lume in one second <1.5 l and 26 had an Sao2 less-than-or-equal-to 92%
. These 26 underwent arterial blood ps analysis. Nine had an arterial
oxygen tension <7.3 kPa all with an arterial carbon dioxide tension (P
aco2) >6 kPa. A further eight had a PaO2 <8 kPa. This produced a sensi
tivity of 100% and specificity of 69% for oximetry in the detection of
Pao2 <7.3 kPa determined by direct arterial puncture and 100% and 86%
respectively for detecting a Pao2 <8 kPa. Although the poor specifici
ty of oximetry in the crucial Pao2 range makes it unsuitable, when use
d alone, for prescription of LTOT, it may prove valuable in selecting
patients who require further definitive arterial blood gas analysis.