CELIPROLOL PNEUMONITIS

We report on a patient who developed hypersensitivity pneumonitis duri ng treatment with the beta-blocker, celiprolol. The clinical picture w as a severe alveolitis, with compromised ps exchange. Inadvertent subs equent rechallenge with celiprolol led to recurrence of the pneumoniti s, 10 weeks after drug readministration. Again, the pneumonitis was fu lly reversible. Lymphocytes were elevated in bronchoalveolar lavage, a nd progressively normalized upon discontinuation of the drug. This cas e is reminiscent of pneumonitis to other beta-blockers, which are revi ewed here.