POSTTRANSFUSION GRAFT-VERSUS-HOST DISEASE IN 2 IMMUNOCOMPETENT PATIENTS

Citation
N. Rubeiz et al., POSTTRANSFUSION GRAFT-VERSUS-HOST DISEASE IN 2 IMMUNOCOMPETENT PATIENTS, Journal of the American Academy of Dermatology, 28(5), 1993, pp. 862-865
Citations number
21
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
01909622
Volume
28
Issue
5
Year of publication
1993
Part
2
Pages
862 - 865
Database
ISI
SICI code
0190-9622(1993)28:5<862:PGDI2I>2.0.ZU;2-J
Abstract
Graft-versus-host disease may occur in certain immunocompromised patie nts after a blood transfusion. The disease is characterized by fever, a skin eruption, gastrointestinal disturbances, liver dysfunction, and bone marrow aplasia. Two cases of fatal graft-versus-host disease are reported. Both patients were immunocompetent and had received transfu sions of nonirradiated blood from their children during surgery. The i mportance of preventing this complication by irradiating blood product s given to patients by their first-degree relatives is underscored.