INHIBITORY POTENCY OF VARIOUS LOCAL-ANESTHETICS IN CARBACHOL-INDUCED AMYLASE RELEASE PARALLELS THAT IN MUSCARINIC RECEPTOR-BINDING IN RAT PANCREATIC ACINI

Authors
IKEI N HABARA Y KANNO T
Citation
N. Ikei et al., INHIBITORY POTENCY OF VARIOUS LOCAL-ANESTHETICS IN CARBACHOL-INDUCED AMYLASE RELEASE PARALLELS THAT IN MUSCARINIC RECEPTOR-BINDING IN RAT PANCREATIC ACINI, Biomedical research, 14(2), 1993, pp. 145-148
Citations number
8
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Biomedical research → ACNP
ISSN journal
03886107
Volume
14
Issue
2
Year of publication
1993
Pages
145 - 148
Database
ISI
SICI code
0388-6107(1993)14:2<145:IPOVLI>2.0.ZU;2-A
Abstract
The order of inhibitory potency of local anesthetics in the carbachol- induced secretory response in rat pancreatic acini was =procaine>dibuc aine>ethyl-aminobenzoate>lidocaine. Almost the identical order of inhi bitory potency was obtained in the binding of [N-methyl-H-3]scopolamin e to muscarinic receptors.