PLASMODIUM-VIVAX VK247 AND VK210 CIRCUMSPOROZOITE PROTEINS IN ANOPHELES MOSQUITOS FROM ANDOAS, PERU

Anopheles mosquitoes captured in Andoas, Peru, a Plasmodium vivax-ende mic area in the Peruvian Amazon region, contained both VK210 and VK247 P. vivax circumsporozoite (CS) proteins. Approximately 0.9% of the 4, 403 mosquitoes tested by enzyme-linked immunosorbent assay were positi ve; 28% and 72% of the positive mosquitoes contained VK210 and VK247 C S proteins, respectively. These findings correlate strongly with a rec ent report of the presence of antibodies in residents of this area tha t recognize the VK210 and VK247 repeats, clearly indicating that both P. vivax CS protein polymorphs are common in the region.