EVIDENCE THAT SUBSTANCE-P RECEPTORS DO NOT EXIST IN MOUSE PAROTID ANDSUBMANDIBULAR ACINAR-CELLS

Authors
TOJYO Y TANIMURA A MATSUMOTO Y
Citation
Y. Tojyo et al., EVIDENCE THAT SUBSTANCE-P RECEPTORS DO NOT EXIST IN MOUSE PAROTID ANDSUBMANDIBULAR ACINAR-CELLS, Archives of oral biology, 38(3), 1993, pp. 269-271
Citations number
15
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
Journal title
Archives of oral biology → ACNP
ISSN journal
00039969
Volume
38
Issue
3
Year of publication
1993
Pages
269 - 271
Database
ISI
SICI code
0003-9969(1993)38:3<269:ETSRDN>2.0.ZU;2-D
Abstract
Substance P (SP) had no effect on cytosolic Ca2+ concentration ([Ca2+] i) and inositol phosphate formation in mouse parotid and submandibular acinar cells, but induced a rapid increase in [Ca2+]i and production of inositol phosphates in rat acinar cells. In addition, SP did not st imulate amylase release from mouse parotid acini, but SP-induced amyla se release was seen in rats. These results indicate that the mouse lac ks SP receptors on parotid and submandibular acinar cells.