The prenatal diagnosis of pulmonary atresia is of particular importanc
e because the affected neonate may be dependent on ductal blood flow t
o the lung, requiring urgent administration of prostaglandins. We revi
ew eight cases studied by ultrasonography in utero. Severe tricuspid r
egurgitation was present in six fetuses. Right ventricular size varied
among cases. Right atrial enlargement was present in seven, usually w
ith tricuspid regurgitation. Failure to identify the main pulmonary-ar
tery or valve on a single examination was not specific. Doppler flow s
tudies were most reliable for the diagnosis by establishing the existe
nce of retrograde flow in the ductus arteriosus from the aorta.