An investigation of possible seasonal patterns in ectopic tubal pregna
ncies was conducted. The computer data utilized were based on all ecto
pic pregnancies, abortions and deliveries (total pregnancies) recorded
in the Department of Obstetrics and Gynecology at the Chaim Sheba Med
ical Center, Israel, between the years 1986 and 1989. Composite monthl
y cohorts of ectopic tubal pregnancies and total pregnancies were cons
tructed for each month of the year, and the probability of an ectopic
pregnancy was estimated. A statistically significant increase in the p
robability of conception rate resulted in ectopic pregnancies which oc
curred during winter and spring, especially in January to June. The pr
obability of ectopic tubal pregnancies was low (0.50%) in September an
d high (1.81-1.42%) in December to January. When we studied primigravi
dae, the same seasonal pattern was observed. The findings of our study
suggest, for the first time, that there is an association between met
eorological and environmental factors, and ectopic pregnancies. These
factors should be considered in the epidemiology of ectopic tubal preg
nancies.