C. Budo et al., CYTOKERATIN IN LENS EPITHELIAL-CELLS AND ITS EFFECT ON ANTERIOR LENS CAPSULE OPACIFICATION, Journal of cataract and refractive surgery, 19(3), 1993, pp. 339-343
Postoperative lens capsule opacification is a complication of extracap
sular cataract extraction. To avoid this problem, we aspirated the epi
thelial cells lining the internal surface of the capsular bag. Anterio
r capsule specimens collected three and six years after the first surg
ical intervention (extracapsular cataract extraction with intercapsula
r implantation of a poly[methyl methacrylate] intraocular lens) and in
vitro studies of epithelial cell cultures revealed the presence of in
tracellular and extracellular cytokeratin. After several years, the cy
tokeratin layers were arranged in a pattern analogous to that of liqui
d crystalline phases and many nonhuman extraocular tissues.