GLUCOSE-METABOLISM BY BROWN TROUT PERIPHERAL-BLOOD LYMPHOCYTES

Glucose metabolism in peripheral blood lymphocytes from the brown trou t Salmo trutta has been studied. Glucose is taken up by means of a sod ium-independent saturable process (K(m) = 10.8 mmol.l-1), as well as b y simple diffusion. Once within the cell, most of glucose is directed to lactate production through either the Embden-Meyerhof pathway or th e hexose-monophosphate shunt. Rates of lactate formation are higher th an rates of CO2 formation. Glutamine does not exert an effect on eithe r glucose uptake or glucose metabolism. The present study provides inf ormation regarding the nature of energy sources for different cell typ es in salmonids.