D. Zaric et al., BLOCKADE OF THE ABDOMINAL MUSCLES MEASURED BY EMG DURING LUMBAR EPIDURAL ANALGESIA WITH ROPIVACAINE - A DOUBLE-BLIND-STUDY, Acta anaesthesiologica Scandinavica, 37(3), 1993, pp. 274-280
A single shot of 20 ml of 1%, 0.75% or 0.5% ropivacaine was administer
ed epidurally (at L2/3 level) to 30 volunteers, in a double-blind mann
er. The blockade of the rectus abdominis muscle was measured quantitat
ively by registration of the average rectified electromyographic signa
l (AREMG) at the T7, T9 and T11 motor segmental levels and with a qual
itative test for blockade of the rectus abdominis muscle (the so-calle
d RAM test). The maximal cranial spread of analgesia, evaluated by the
pin-prick method, was not significantly different for the three conce
ntrations (T8-T10 dermatome; median value). The intensity of motor blo
ckade, measured by the AREMG method, increased progressively from the
T7 segment and caudally with all three concentrations. The blockade wa
s partial (i.e. 85-25% of baseline AREMG activity was present at its m
aximum) in all subjects. When the effect of the three concentrations o
f ropivacaine was compared at the same segmental level, the intensity
and duration of maximal motor blockade seemed to be dose-dependent, bu
t the difference was not statistically significant. The total duration
of motor blockade was shorter with the 0.5% solution than with the hi
gher concentrations. The AREMG method gave a more exact and graded pic
ture of blockade of the rectus abdominis muscle than the RAM test. The
duration of sensory blockade did not outlast motor blockade at any le
vel. In half of our subjects the maximal spread of sensory blockade wa
s either equal to or higher than the spread of partial motor block. In
the other half, this relationship was reversed - the maximal cranial
level of partial motor block was 1-4 segments higher than the maximal
level of analgesia.