2 DEVELOPMENTALLY REGULATED MESSENGER-RNAS ENCODING ACTIN-BINDING PROTEINS IN PHYSARUM-POLYCEPHALUM

Authors
STPIERRE B COUTURE C LAROCHE A PALLOTTA D
Citation
B. Stpierre et al., 2 DEVELOPMENTALLY REGULATED MESSENGER-RNAS ENCODING ACTIN-BINDING PROTEINS IN PHYSARUM-POLYCEPHALUM, Biochimica et biophysica acta, 1173(1), 1993, pp. 107-110
Citations number
22
Categorie Soggetti
Biophysics,Biology
Journal title
Biochimica et biophysica acta → ACNP
ISSN journal
00063002
Volume
1173
Issue
1
Year of publication
1993
Pages
107 - 110
Database
ISI
SICI code
0006-3002(1993)1173:1<107:2DRMEA>2.0.ZU;2-Y
Abstract
A cDNA library from amoebae of Physarum polycephalum was screened by d ifferential hybridization. Two clones contained inserts for mRNAs pres ent in amoebae and absent in plasmodia. The LAV3-4 cDNA encodes a 402 aa protein (ABP-46) that shows sequence similarity to the actin bindin g site in the N-terminal region of the alpha-actinin family. The LAV3- 5 cDNA is 76% identical to the Dictlyostelium actin bundling protein, which cross-links and stabilizes actin filaments in amoebal filopodia.