THEORY OF CHIRAL SEPARATION IN CAPILLARY ELECTROPHORESIS

The resolution of a pair of enantiomers in chiral capillary electropho resis (CE) is described by the use of a simple model. The model shows the importance of maximising the electrophoretic mobility difference b etween the two enantiomers, and also the influence of electroosmotic m obility. The theory is supported by results obtained with ephedrine, a tenolol and practolol.