DIFFERENTIAL BINDING OF TIOCONAZOLE ENANTIOMERS TO HYDROXYPROPYL-BETA-CYCLODEXTRIN STUDIED BY CAPILLARY ELECTROPHORESIS

Authors
PENN SG GOODALL DM LORAN JS
Citation
Sg. Penn et al., DIFFERENTIAL BINDING OF TIOCONAZOLE ENANTIOMERS TO HYDROXYPROPYL-BETA-CYCLODEXTRIN STUDIED BY CAPILLARY ELECTROPHORESIS, Journal of chromatography, 636(1), 1993, pp. 149-152
Citations number
12
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of chromatography → ACNP
Volume
636
Issue
1
Year of publication
1993
Pages
149 - 152
Database
ISI
SICI code
Abstract
Capillary electrophoresis has been used to determine binding constants of tioconazole enantiomers with hydroxypropyl-beta-cyclodexrin (HP-be ta-CD), after correcting for changes in mobility with increasing visco sity. The predicted and observed values of enantiomeric mobility diffe rence were found to be maximum at a concentration of HP-beta-CD equal to the reciprocal of the average binding constant.