Pyogenic hepatic abscess is a rare condition associated with severe se
quelae. The diagnosis may be obvious in patients with fever and leukoc
ytosis who are clearly predisposed to this infectious complication. In
patients without known risk factors, diagnosis and treatment are ofte
n delayed, usually until numerous health care resources have been cons
ulted. The evaluation of occult hepatic abscess may be improved by a h
istory directed at identifying predisposing conditions, by an appropri
ate physical examination and by the use of computed tomographic scanni
ng. The standard treatment for pyogenic hepatic abscess is percutaneou
s or open drainage, accompanied by broad-spectrum antibiotic therapy.