HUMAN UTERINE PROTEIN IN RELATION TO INFERTILITY

The concentration of electrophoretic protein in the uterine fluid of i nfertile women is significantly higher at all the phases of the menstr ual cycle, except at phase I where it is significantly (p < 0.01) lowe r than parous women. At phase III (ovulatory phase) the concentration of electrophoretic protein (2812.00 mug/ml) is maximum in infertiles, and shows a highly significant (p < 0.001) increase over that of parou s women (954.85 mug/ml). The highest level of electrophoretic protein at phase III in infertile women is due to maximum increase in anodic ( electronegative) protein at this stage. This suggests that significant (p < 0.001) increase in concentration of anodic protein in the uterin e fluid of infertile women at the ovulatory phase adds negative charge on sperm membrane that may possibly affect the capacitation of sperma tozoa, thus causing infertility in women.