THE FORMS AND FUNCTIONS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE

Authors
MONDER C
Citation
C. Monder, THE FORMS AND FUNCTIONS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, Journal of steroid biochemistry and molecular biology, 45(1-3), 1993, pp. 161-165
Citations number
19
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Journal of steroid biochemistry and molecular biology → ACNP
ISSN journal
09600760
Volume
45
Issue
1-3
Year of publication
1993
Pages
161 - 165
Database
ISI
SICI code
0960-0760(1993)45:1-3<161:TFAFO1>2.0.ZU;2-Q
Abstract
In this review, we consider the relationship between the structure and function of 11beta-hydroxysteroid dehydrogenase (11-HSD) purified fro m rat liver. The rat liver enzyme is a single domain glycoprotein with a unique active site and belongs to the short chain alcohol dehydroge nase family. Evidence supporting the presence in other tissues of 11-H SD isoforms is discussed.