J. Gorcsan et al., ONLINE ESTIMATION OF STROKE VOLUME BY MEANS OF ECHOCARDIOGRAPHIC AUTOMATED BORDER DETECTION IN THE CANINE LEFT-VENTRICLE, The American heart journal, 125(5), 1993, pp. 1316-1323
Echocardiographic automated border detection (ABD) is a new on-line te
chnique that can determine the interface between blood and myocardial
tissue and calculate left ventricular (LV) cavity area in real time. T
he objective of this study was to determine whether ABD measurements o
f the LV cavity area could be used to estimate LV stroke volume at bas
al conditions and during large changes in LV stroke volume induced by
inferior vena caval occlusions in an open-chest canine model. Seven do
gs had LV stroke volume measured by electromagnetic flow from the asce
nding aorta with epicardial recordings of ABD echocardiographic area a
t the midventricular short-axis level. Simultaneous beats of stroke vo
lume were recorded along with ABD echo area during baseline apnea and
during IVC occlusions. Neither ABD echo stroke area nor stroke volume
varied significantly during apnea baseline. Changes in stroke area wer
e closely correlated with changes in stroke volume for 540 matched bea
ts from 24 IVC occlusions: R = 0.93, standard error of the estimate =
5%, y = 0.92x + 0.4 (p < 0.001). Echocardiographic ABD appears to be a
promising new on-line method of determining rapid alterations in LV s
troke volume; it also has potential applications to multiple investiga
tional and clinical settings.