SYNTHESIS AND PROPERTIES OF PHOSPHOLIPID ANALOGOUS POLY(ACRYLAMIDE) CONTAINING VITAMIN-E MOIETY

An amphiphilic acrylamide monomer containing a vitamin E moiety as the hydrophobic group and a phosphatidylcholine analogue as the hydrophil ic group was newly synthesized in high yield. The radical polymerizati on was carried out in the presence of alpha, alpha'-azobisisobutyronit rile as an initiator. The obtained monomer and homopolymer were charac terized by H-1 NMR, IR, and melting points. A stacked bilayer structur e was proposed for homopolymer from x-ray diffraction analysis. Furthe rmore, monolayers of the homopolymer were prepared on the surface of w ater and were investigated at different temperatures.