EFFECTS OF ANTICONVULSANT DRUGS ON THYROID-HORMONES IN EPILEPTIC CHILDREN

Authors
DEDA G AKINCI A TEZIC T KARAGOL U
Citation
G. Deda et al., EFFECTS OF ANTICONVULSANT DRUGS ON THYROID-HORMONES IN EPILEPTIC CHILDREN, Turkish Journal of Pediatrics, 34(4), 1992, pp. 239-244
Citations number
NO
Categorie Soggetti
Pediatrics
Journal title
Turkish Journal of Pediatrics → ACNP
ISSN journal
00414301
Volume
34
Issue
4
Year of publication
1992
Pages
239 - 244
Database
ISI
SICI code
0041-4301(1992)34:4<239:EOADOT>2.0.ZU;2-C
Abstract
Serum total and free thyroid hormones, reverse T3 (rT3), thyroxin bind ing globulin (TBG) and thyroid stimulating hormone (TSH) concentration s were measured in 35 epileptic patients receiving anticonvulsants (ph enobarbitone, phenytoin). There was a significant reduction found in t otal thyroxine (TT4), free thyroxine (FT4), total triiodothyronine (TT 3), free triiodothyronine (FT3) and rT3 in the group treated with, phe nytoin. The thyroid hormone levels were within normal limits in the gr oup receiving phenobarbitone.