The results of microsurgical epididymovasostomy for congenital and acq
uired vasoepididymal obstruction were retrospectively reviewed in 22 p
atients in an attempt to determine what preoperative or intraoperative
factors might predict surgical success. The overall success rate, def
ined as sperm on postoperative semen analysis, was 48%. The presence o
f sperm on an intraoperative touch preparation from the epididymis was
significantly correlated with response (chi-square 3.24, p < 0.10) an
d no patient without sperm on touch preparation had sperm on subsequen
t semen analyses. Testicular biopsy positive for spermatogenesis and p
resence of motile sperm on intraoperative touch preparation were not s
tatistically significant predictors of response. These results suggest
that presence or absence of sperm on intraoperative touch preparation
is the only significant prognosticator of successful microsurgical ep
ididymovasostomy.