ACUTE-RENAL-FAILURE AFTER EXERCISE IN A CHILD WITH RENAL HYPOURICAEMIA

We describe a 12-year-old boy with renal hypouricaemia who presented w ith acute renal failure after a 6-h sports training session. Back and loin pain were noted at presentation. Although serum creatinine and bl ood urea nitrogen were-elevated, the serum uric acid concentration was normal (2.6 mg/dl). This decreased to 0.3 mg/dl after recovery. The p yrazinamide and probenecid tests revealed that the cause of renal hypo uricaemia in this patient was totally defective uric acid reabsorption . Acute renal failure after exercise is a rare but serious complicatio n in paediatric patients with renal hypouricaemia.