An educational program for hospital pharmacists in and near Vermont is
described and its impact on departmental clinical practice evaluated.
Pharmacists were instructed by practitioners from a single institutio
n in basic pharmacokinetics, practice guidelines for aminoglycoside th
erapy, and use of a computer program for aminoglycoside dosage determi
nation. Participants completed a multiple-choice precourse test, a sim
ilar postcourse test, and a third test six months after class completi
on. Test scores were compared with those from a control group of pharm
acists. Pharmacy directors from study group hospitals completed questi
onnaires measuring aminoglycoside clinical services before and six mon
ths after the program. Compared with the control group, participants s
cored higher on the postcourse tests. Results from the questionnaire i
ndicate that the program affected clinical practice in almost all part
icipating pharmacy departments. A consistent pharmacokinetic strategy
for reviewing aminoglycoside dosages and evaluating serum aminoglycosi
de concentrations is now practiced in most Vermont hospitals. An educa
tional program originating in one hospital can expand pharmacists, kno
wledge and influence departmental clinical practice throughout a regio
n.