Although not rare, paraneoplastic syndromes develop in a minority of c
ancer patients. Their exact frequency seems to be under estimated. The
se syndromes are hereby described. Their clinical usefulness is of gre
at importance: they can be the first sign of a malignancy and can be u
sed as tumor markers. The diagnosis of paraneoplastic syndromes is oft
en difficult. A ''diagnosis score'' is proposed to establish this diag
nosis easier.