TABLETS OF HAMAMELIS DRY EXTRACT BY DIRECT COMPRESSION - COMPARATIVE-STUDY OF NATURAL STARCHES AND STARCH DERIVATIVES

Authors
VENNAT B GROSS D POURRAT A POURRAT H
Citation
B. Vennat et al., TABLETS OF HAMAMELIS DRY EXTRACT BY DIRECT COMPRESSION - COMPARATIVE-STUDY OF NATURAL STARCHES AND STARCH DERIVATIVES, Drug development and industrial pharmacy, 19(11), 1993, pp. 1357-1368
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Drug development and industrial pharmacy → ACNP
ISSN journal
03639045
Volume
19
Issue
11
Year of publication
1993
Pages
1357 - 1368
Database
ISI
SICI code
0363-9045(1993)19:11<1357:TOHDEB>2.0.ZU;2-Y
Abstract
Tablets of hamamelis dry extract are made by direct compression. The r heological properties of natural starches and of various starch deriva tives (split starches, pregelatinized starches, starch glycolates...) are compared. 50 mg hamamelis dry extract (20 % w/w) formulations were prepared with these different disintegrants; for each formulation mec hanical properties of both powder mixture and resulting tablets were a ssessed.