This study addresses the effect of strong routine associations (captur
e errors) in hindering the control of on-line serial or sequencing tas
ks. Patients with focal frontal lobe lesions were significantly inferi
or to normal control subjects and patients with posterior brain lesion
s, when conditions that may lead to capture errors were present. The r
esults suggest that the primary dysfunction exhibited by patients with
frontal lobe lesions on capture error tasks may lie not in the diseng
agement from the invalid associations but in focusing attention to alt
ernative strategies of response.