C. Planche et al., ANATOMIC REPAIR OF TRANSPOSITION OF GREAT-ARTERIES WITH VENTRICULAR SEPTAL-DEFECT AND AORTIC-ARCH OBSTRUCTION - ONE-STAGE VERSUS 2-STAGE PROCEDURE, Journal of thoracic and cardiovascular surgery, 105(5), 1993, pp. 925-933
Between September 1, 1982, and March 1, 1992, 40 patients underwent an
atomic repair of transposition of the great arteries, ventricular sept
al defect, and aortic arch obstruction. In group I, 26 patients (65%)
underwent repair in a two-stage procedure, phases A and B. Phase A inc
luded repair of the aortic arch obstruction with (16 patients) or with
out (10 patients) pulmonary artery banding through a left thoracotomy
(mean age 18.7 +/- 23.4 days). There were three deaths and three reope
rations. Phase B included an arterial switch operation with closure of
the ventricular septal defect (mean age 95.5 +/- 122 days). There wer
e five early deaths and two late deaths. Eight patients required reope
ration. Mean delay between phase A and phase B was 77.5 +/- 109 days.
In group I, there were eight early and two late deaths, and 11 patient
s required reoperation. The mean stay in the intensive care unit was 2
4.7 +/- 20 days. Mean follow-up of 59.6 +/- 21.4 months was completed
in all survivors. All but one were in New York Heart Association class
I without medication. Actuarial survival rate and rate of freedom fro
m reoperation at 5 years were 57.5% and 49.9%, respectively. In group
II, 14 patients (35%) had a one-stage procedure through midsternotomy:
an arterial switch operation with closure of the ventricular septal d
efect and repair of the aortic arch obstruction (mean age 10.2 +/- 5.5
days). There were two early deaths (14.2%) and one late death after r
eoperation for overlooked multiple ventricular septal defects. Two pat
ients required reoperation. The mean stay in the intensive care unit w
as 11.7 +/- 2.5 days. Mean follow-up of 22.4 +/- 16.7 months was achie
ved in all survivors. They were all in New York Heart Association clas
s I without medication. Actuarial survival rate and rate of freedom fr
om reoperation at 3 years were 78.5% and 81.5%, respectively. The one-
stage procedure allowed complete repair in neonates without the need f
or multiple operations. We believe that it may decrease early mortalit
y rates (14.2% versus 30.7%), reduce the reoperation rate and cumulati
ve stay in the intensive care unit (11.7 days versus 24.7 days, p = No
t significant), and significantly decrease the overall rate of morbidi
ty (p < 0.01). However, requirements for surgical intervention with a
one-stage or a two-stage procedure must include accurate assessments o
f intracardiac and aortic arch anatomy.