Four trials, using 48 European breed cattle, were conducted to evaluat
e the efficacy of abamectin against the louse species Linognathus vitu
li, Haematopinus eurysternus and Damalinia bovis and against the mange
mites Sarcoptes scabiei var bovis and Psoroptes ovis. Animals were al
located by restricted randomisation based on parasite counts to treatm
ent with abamectin at a dose of 200 mug/kg given subcutaneously or to
an untreated control group. Ectoparasites were counted before treatmen
t and at weekly intervals thereafter for eight weeks. L vituli, H eury
sternus and S scabiei var bovis were eliminated (P<0.05) by day 7 afte
r abamectin treatment. An efficacy of more than 99 per cent was record
ed against P ovis mange mites. The biting louse D bovis was not contro
lled. Abamectin treatment increased the weight gain of cattle infested
with ectoparasites.