STATISTICAL-ANALYSIS OF ANIMAL CANCER CHEMOPREVENTION EXPERIMENTS

Citation
Ls. Freedman et al., STATISTICAL-ANALYSIS OF ANIMAL CANCER CHEMOPREVENTION EXPERIMENTS, Biometrics, 49(1), 1993, pp. 259-268
Citations number
6
Categorie Soggetti
Statistic & Probability","Statistic & Probability
Journal title
ISSN journal
0006341X
Volume
49
Issue
1
Year of publication
1993
Pages
259 - 268
Database
ISI
SICI code
0006-341X(1993)49:1<259:SOACCE>2.0.ZU;2-0
Abstract
We explore the use of a statistical model proposed by Kokoska (1987, B iometrics 43, 525-534) for the analysis of animal cancer chemopreventi on experiments. We show, using an example, that the results derived fr om the method can be sensitive to the parametric forms of the distribu tions that are assumed, particularly to the distribution of the number of tumors per animal. We propose goodness-of-fit tests to aid in the choice of the distributions.