B. Rossi et Mg. Vignocchi, METHODOLOGICAL CONSIDERATIONS ON THE USE OF THE BLINK REFLEX R3 COMPONENT IN THE ASSESSMENT OF PAIN IN MAN, Italian journal of neurological sciences, 14(3), 1993, pp. 217-224
We define the principal Physiological properties of the nociceptive co
mponent R3 of the blink reflex (b.r.) on electrical stimulation of the
supraorbital nerve, with the aim of supplying some rules for its use
in the analysis of pain in man. We explore the relationship between th
e threshold (th) of R3 and that of pain on stimulation of the trigemin
al nerve and the extent to which R3 is modulated by habituation and at
tentional levels. Both pain th and R3 th correlate significantly with
age. The R3 th was always.higher than the R2 th. Habituation definitel
y decreases the amplitude of R3, which easily disappears. Focusing of
attention on the stimulus sharply inhibits R3 while distraction increa
ses it. Our findings emphasize the need to take all these aspects into
account when designing protocols for the study of pain mechanisms bas
ed on the R3 reflex component.