Ac. Bruni et al., THE POWER OF SYSTEMATIC GENEALOGICAL STUDY IN FAMILIAL ALZHEIMER-DISEASE, Italian journal of neurological sciences, 14(3), 1993, pp. 239-244
Several kindreds (N, C, To and RB) with familial Alzheimer disease (FA
D) from the same small area of Calabria are currently under study. Rec
ently two of us (F.M. and L.F-S.) identified a family in Milan (FJ01)
made up of 3 siblings whose parents were of Calabrian origin. Through
a subsequent systematic or blanket genealogical study a link has been
traced between kindreds To and FJ01. We discuss the relevance of these
results to genetic studies.