THE POWER OF SYSTEMATIC GENEALOGICAL STUDY IN FAMILIAL ALZHEIMER-DISEASE

Authors
BRUNI AC MONTESI MP RAINERO I FERINISTRAMBI L MACCIARDI F PINESSI L GEI G FRAGIACOMO D BERGAMINI L
Citation
Ac. Bruni et al., THE POWER OF SYSTEMATIC GENEALOGICAL STUDY IN FAMILIAL ALZHEIMER-DISEASE, Italian journal of neurological sciences, 14(3), 1993, pp. 239-244
Citations number
10
Categorie Soggetti
Neurosciences
Journal title
Italian journal of neurological sciences → ACNP
ISSN journal
03920461
Volume
14
Issue
3
Year of publication
1993
Pages
239 - 244
Database
ISI
SICI code
0392-0461(1993)14:3<239:TPOSGS>2.0.ZU;2-0
Abstract
Several kindreds (N, C, To and RB) with familial Alzheimer disease (FA D) from the same small area of Calabria are currently under study. Rec ently two of us (F.M. and L.F-S.) identified a family in Milan (FJ01) made up of 3 siblings whose parents were of Calabrian origin. Through a subsequent systematic or blanket genealogical study a link has been traced between kindreds To and FJ01. We discuss the relevance of these results to genetic studies.