SYNTHESIS OF SHIKALKIN AND CERTAIN RELATED-COMPOUNDS

Authors
NOVIKOV VL BALANEVA NN MOISEENKOV AM ELYAKOV GB
Citation
Vl. Novikov et al., SYNTHESIS OF SHIKALKIN AND CERTAIN RELATED-COMPOUNDS, Bulletin of the Russian Academy of Sciences, Division of Chemical Sciences, 41(8), 1992, pp. 1485-1494
Citations number
31
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Russian Academy of Sciences, Division of Chemical Sciences → ACNP
ISSN journal
10635211
Volume
41
Issue
8
Year of publication
1992
Part
2
Pages
1485 - 1494
Database
ISI
SICI code
1063-5211(1992)41:8<1485:SOSACR>2.0.ZU;2-Z
Abstract
A successful total synthesis of a biologically active pigment from pla nts of the Boraginaceae family was carried out with naphthazarine as t he starting material, and using the 1,4,5,8-tetramethoxynaphthalene, t he corresponding 2-vinyl derivative and its epoxide or a cyclopropane adduct with diazoacetic ester at the key stages. In the course of deve loping the scheme of the synthesis of shikalkin, its three analogs wer e obtained, differing in the nature of the monoterpenoid side chain.