NEW IMINIUM COMPOUNDS AGAINST BACTERIA AND FUNGI .29. 3-ALKOXYMETHYL-1-ETHYLBENZIMIDAZOLIUM, 3-ALKYLTHIOMETHYL-1-ETHYLBENZIMIDAZOLIUM, 3-ALKOXYMETHYL-1-BUTYLBENZIMIDAZOLIUM AND 3-ALKYLTHIOMETHYL-1-BUTYLBENZIMIDAZOLIUM CHLORIDES

Authors
PERNAK J SKRZYPCZAK A MICHALAK L JEDRASZCZYK J KRYSINSKI J KAZMIERCZAK M MROWCZYNSKI B
Citation
J. Pernak et al., NEW IMINIUM COMPOUNDS AGAINST BACTERIA AND FUNGI .29. 3-ALKOXYMETHYL-1-ETHYLBENZIMIDAZOLIUM, 3-ALKYLTHIOMETHYL-1-ETHYLBENZIMIDAZOLIUM, 3-ALKOXYMETHYL-1-BUTYLBENZIMIDAZOLIUM AND 3-ALKYLTHIOMETHYL-1-BUTYLBENZIMIDAZOLIUM CHLORIDES, Archiv der pharmazie, 326(4), 1993, pp. 237-240
Citations number
11
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
326
Issue
4
Year of publication
1993
Pages
237 - 240
Database
ISI
SICI code
0365-6233(1993)326:4<237:NICABA>2.0.ZU;2-0
Abstract
Syntheses and antimicrobial activity of 3-alkoxymethyl-1-ethyl-, 3-alk ylthiomethyl-1-ethyl-, 3-alkoxymethyl-1-butyl-, and 3-alkylthiomethyl- 1-butylbenzimidazolium chlorides are described. The compounds were obt ained by reaction of 1-ethyl- or 1-butylbenzimidazole with chloromethy lalkyl ethers or chloromethylalkyl sulfide. Antibacterial properties w ere tested on 13 strains of bacteria and fungi. 3-Dodecylthio-methyl-1 -ethyl-benzimidazolium chloride exhibited the highest antibacterial ac tivity.