EFFECT OF SIALOADENECTOMY ON THE CARRIAGE OF CANDIDA-ALBICANS IN THE MOUTHS OF RATS

Authors
JORGE AOC TOTTI MAG DEALMEIDA OP SCULLY C
Citation
Aoc. Jorge et al., EFFECT OF SIALOADENECTOMY ON THE CARRIAGE OF CANDIDA-ALBICANS IN THE MOUTHS OF RATS, Journal of oral pathology & medicine, 22(3), 1993, pp. 138-140
Citations number
26
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
Journal title
Journal of oral pathology & medicine → ACNP
ISSN journal
09042512
Volume
22
Issue
3
Year of publication
1993
Pages
138 - 140
Database
ISI
SICI code
0904-2512(1993)22:3<138:EOSOTC>2.0.ZU;2-H
Abstract
Xerostomia provoked in rats by surgical removal of the major salivary glands significantly increased oral carriage of Candida albicans. Five weeks after 3 oral inoculations of 10(8) CFU, C albicans were found i n the mouths in 50% of normal animals but after 8 weeks in none. In xe rostomic rats, 100% had oral C. albicans after 5 weeks and after 18 we eks, 66.6% still harboured yeasts. Over the whole experimental period the amount of C. albicans was greater in the mouths of sialoadenectomi zed than in normal rats.