CRUDE EXTRACTS AND 2 LINEAR DITERPENES FROM CYSTOSEIRA-BALEARICA AND THEIR ACTIVITY

Crude extracts of Cystoseira balearica were submitted to pharmacologic al investigations. The chloroform-methanol residue caused relaxation o f the rat aortic musculature and an inhibitory action on the guinea pi g atria. The fractionation of this crude extract gave two active diter penoids, eleganolone (1) and elegandiol (2), the latter has not previo usly been isolated from this alga. These pure components, never before tested, showed a higher activity when compared with the crude residue .