INTERFERON-ALFA-2B FOR DECOMPENSATED LIVER-DISEASE CAUSED BY EITHER CHRONIC HEPATITIS-B OR HEPATITIS-C - PRELIMINARY-RESULTS OF A PILOT-STUDY

Authors
DIMOPOULOU M FAFOUTIS K BASILIOU K KETIKOGLOU J KARVOUNTZIS G
Citation
M. Dimopoulou et al., INTERFERON-ALFA-2B FOR DECOMPENSATED LIVER-DISEASE CAUSED BY EITHER CHRONIC HEPATITIS-B OR HEPATITIS-C - PRELIMINARY-RESULTS OF A PILOT-STUDY, Gut, 34(2), 1993, pp. 104-105
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Gut → ACNP
ISSN journal
00175749
Volume
34
Issue
2
Year of publication
1993
Supplement
S
Pages
104 - 105
Database
ISI
SICI code
0017-5749(1993)34:2<104:IFDLCB>2.0.ZU;2-9
Abstract
This pilot study was designed to assess the tolerance and effectivenes s of interferon alfa-2b in patients with decompensated liver disease c aused by chronic hepatitis B (n=7) or C (n=5). Preliminary results sug gest that patients may benefit from small doses of interferon (improve ment in liver function tests and reduction in alanine aminotransferase ), although the decreased tolerance and dose dependent increase in sid e effects in these patients with liver disease underlines the need for close follow up and the dose adjustment of interferon treatment.