ZIDOVUDINE PLUS INTERFERON-ALFA-2B TREATMENT IN PATIENTS WITH HIV ANDCHRONIC ACTIVE VIRAL-HEPATITIS

Authors
VISCO G ALBA L GRISETTI S GUARASCIO P NARCISO P SETTE P STRUGLIA C TOSSINI G TOZZI V
Citation
G. Visco et al., ZIDOVUDINE PLUS INTERFERON-ALFA-2B TREATMENT IN PATIENTS WITH HIV ANDCHRONIC ACTIVE VIRAL-HEPATITIS, Gut, 34(2), 1993, pp. 107-108
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Gut → ACNP
ISSN journal
00175749
Volume
34
Issue
2
Year of publication
1993
Supplement
S
Pages
107 - 108
Database
ISI
SICI code
0017-5749(1993)34:2<107:ZPITIP>2.0.ZU;2-U
Abstract
Results are reported for a small study of 11 patients positive for HIV and with chronic active viral hepatitis. Low dose zidovudine/interfer on alfa-2b combined treatment produced a general reduction in alanine aminotransferase activities and increased the CD4 lymphocyte count, he patitis B e seroconversion, and the loss of HIV p24 antigen. The treat ment was well tolerated and progression of HIV disease was not seen.