RECOMBINANT INTERFERON-ALFA-2B TREATMENT IN CHRONIC NON-A, NON-B TYPE-C HEPATITIS

Citation
V. Deconca et al., RECOMBINANT INTERFERON-ALFA-2B TREATMENT IN CHRONIC NON-A, NON-B TYPE-C HEPATITIS, Gut, 34(2), 1993, pp. 126-126
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
GutACNP
ISSN journal
00175749
Volume
34
Issue
2
Year of publication
1993
Supplement
S
Pages
126 - 126
Database
ISI
SICI code
0017-5749(1993)34:2<126:RITICN>2.0.ZU;2-E
Abstract
In a study of 60 patients with non-A, non-B/type C (NANB/C) chronic he patitis alanine aminotransferase (ALT) activities returned to normal a fter treatment with interferon alfa-2b (3 million units for six months ) in 70.7% and 29.3% did not respond. The response was maintained duri ng four to six months, follow up in 41.4% of patients. Liver biopsy sp ecimen showed histological improvement in all patients surveyed. Treat ment was well tolerated with only mild side effects.