A. Fleurant et al., HIGHLY DIASTEREOMER SELECTIVE ACYLATION OF 2,5-DIALKYLPYRROLIDINES - A VERSATILE ROUTE TO TRANS-2,5-DISUBSTITUTED CYCLIC AMINO-ALCOHOLS, Heterocycles, 36(5), 1993, pp. 929-932
Diastereoisomeric mixtures of cis- and trans- disubstituted pyrrolidin
es are separated by kinetically controlled acylation with benzyl chlor
oformate.