NEW ALKALOIDS FROM CONSOLIDA-HELLESPONTICA

From the aerial parts of Consolida hellespontica (Boiss.) Chater we ha ve isolated the new diterpenoid alkaloids chellespontine (1) and aziti ne (4). The norditerpenoid alkaloid 1-O-methyldelphisine (7) has not b een reported earlier as occurring in nature, and the aporphine alkaloi d (+)-corydine (11) has been isolated for the first time in the Ranunc ulaceae family. Besides these, the known alkaloids delphinine (8), del phisine (9) and bullatine C (14-acetylneoline) (10) have been isolated from this plant. The structures of these alkaloids were established b y chemical correlation and spectroscopic studies.