DISSOCIATION OF BLOOD-PRESSURE AND ALBUMINURIA IN NORMAL SUBJECTS INFUSED WITH ANGIOTENSIN-II AND NORADRENALINE

Authors
COHEN N PHILLIPS P GILBERT R JERUMS G
Citation
N. Cohen et al., DISSOCIATION OF BLOOD-PRESSURE AND ALBUMINURIA IN NORMAL SUBJECTS INFUSED WITH ANGIOTENSIN-II AND NORADRENALINE, Clinical and experimental pharmacology and physiology, 20(5), 1993, pp. 317-319
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy",Physiology
Journal title
Clinical and experimental pharmacology and physiology → ACNP
ISSN journal
03051870
Volume
20
Issue
5
Year of publication
1993
Pages
317 - 319
Database
ISI
SICI code
0305-1870(1993)20:5<317:DOBAAI>2.0.ZU;2-8
Abstract
1. Albuminuria is a predictor of diabetic renal disease and atheroscle rosis. Changes in blood pressure (BP) may influence albuminuria. 2. Th e effect of acute BP elevation on albumin excretion rates (AER) using noradrenaline (NA) and angiotensin II (AII) infusions in six normal su bjects was examined. 3. The average rise in BP during a 120 min infusi on was 23 mmHg for AII and 16 mmHg for NA. 4. There was a marked disso ciation between AER and BP levels in both AII and NA infusions. 5. Pre viously described correlations between BP and AER in ambulatory BP stu dies may be explained by other factors such as exercise and postural c hanges.