CARDIOVASCULAR EFFECTS OF A TRANDOLAPRIL VERAPAMIL COMBINATION IN PATIENTS WITH MILD-TO-MODERATE ESSENTIAL-HYPERTENSION/

Authors
AEPFELBACHER FC MESSERLI FH NUNEZ E MICHALEWICZ L
Citation
Fc. Aepfelbacher et al., CARDIOVASCULAR EFFECTS OF A TRANDOLAPRIL VERAPAMIL COMBINATION IN PATIENTS WITH MILD-TO-MODERATE ESSENTIAL-HYPERTENSION/, The American journal of cardiology, 79(6), 1997, pp. 826
Citations number
20
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
79
Issue
6
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)79:6<826:CEOATV>2.0.ZU;2-#
Abstract
The cardiovascular effects of a combination of trandolapril and verapa mil were evaluated in 14 patients with mild to moderate essential hype rtension. This combination therapy decreased arterial pressure mainly through a decrease in total peripheral resistance without causing an i ncrease in heart rate or cardiac output: left ventricular mass was sig nificantly reduced, cardiac systolic function improved, and plasma vol ume and renal blood flow remained unchanged.