Esophageal perforations in liver transplant patients are associated wi
th high morbidity and mortality (1). We describe 2 cases of esophageal
perforations following sclerotherapy for variceal bleeding. Diagnosis
was made 20 and 6 days post-sclerotherapy and 16 and 4 days post-live
r transplant. Both cases were treated with pharyngeal drainage or dive
rsion, pleural drainage, gastrostomy, intravenous hyperalimentation, e
nteral feeding, antibiotics, withdrawal of steroids and reduction of i
mmunosuppressive drugs. In both cases closure of the fistula occurred
within 10 to 14 days after detection and with no sip of esophageal str
icture formation. We believe this approach to esophageal perforations
may be used safely in liver transplantation patients if close monitori
ng of potential complications is adhered to. This approach obviates th
e risks of thoracotomy without compromising the basic surgical princip
les of exclusion and drainage.